4-CMTB

Tocris Bioscience, part of Bio-Techne | Catalog # 4642

FFA2 agonist; also exhibits positive allosteric modulatory activity
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Key Product Details

Description

FFA2 agonist; also exhibits positive allosteric modulatory activity

View all Free Fatty Acid Receptor Agonists »

Product Description

4-CMTB is a free fatty acid receptor FFA2 agonist (pEC50 = 6.38) and positive allosteric modulator. Binds at a site distinct from the orthosteric site; modulates the activity of short-chain fatty acids at FFA2 via the FFA2 second extracellular loop (ECL2).

Product Specifications

Molecular Weight

294.80

Formula

C14H15ClN2OS

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

4-chloro-α-(1-methylethyl)-N-2-thiazolylbenzeneacetamide

CAS Number

300851-67-6

PubChem ID

4307629

InChI Key

AZYDQCGCBQYFSE-UHFFFAOYSA-N

SMILES

ClC1=CC=C(C(C(C)C)C(NC2=NC=CS2)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 29.48 100
Ethanol 5.9 20

Preparing Stock Solutions for 4-CMTB

The following data is based on the product molecular weight 294.80

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.39 mL 16.96 mL 33.92 mL
5 mM 0.68 mL 3.39 mL 6.78 mL
10 mM 0.34 mL 1.70 mL 3.39 mL
50 mM 0.07 mL 0.34 mL 0.68 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for 4-CMTB

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for 4-CMTB

For research use only

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