1-Hex-GlcNAlk
Tocris Bioscience, part of Bio-Techne | Catalog # 7751
Metabolic chemical reporter for studying glycosylation and glycoproteins
Key Product Details
Description
Metabolic chemical reporter for studying glycosylation and glycoproteins
Product Description
1-Hex-GlcNAlk is a metabolic chemical reporter (MCR) for studying glycoproteins and glycosylation; it comprises GlcNAlk functionalized at the anomeric position with hexanoic acid. 1-Hex-GlcNAlk exhibits time- and concentration-dependent specific enzymatic labeling of proteins in HeLa cells, with negligible background labeling detected in cell lysates.Product Specifications
Molecular Weight
357.40
Formula
C17H27NO7
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
(2S,3R,4R,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(pent-4-ynamido)tetrahydro-2H-pyran-2-yl hexanoate
CAS Number
2863607-71-8
InChI Key
PJQZXSANZZIQIK-YFTGLANFSA-N
SMILES
OC[C@H]1O[C@@H](OC(CCCCC)=O)[C@H](NC(CCC#C)=O)[C@@H](O)[C@@H]1O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 35.74 | 100 |
Preparing Stock Solutions
for 1-Hex-GlcNAlk
The following data is based on the product molecular weight 357.40
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.80 mL | 13.99 mL | 27.98 mL |
| 5 mM | 0.56 mL | 2.80 mL | 5.60 mL |
| 10 mM | 0.28 mL | 1.40 mL | 2.80 mL |
| 50 mM | 0.06 mL | 0.28 mL | 0.56 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Pedowitz Anomeric fatty acid functionalization prevents nonenzymatic S-glycosylation by monosaccharide metabolic chemical reporters. ACS Chem Biol 2021 PMID: 34282887
Product Specific Notices for 1-Hex-GlcNAlk
For research use only
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