1-Deazaadenosine
Tocris Bioscience, part of Bio-Techne | Catalog # 4488
Adenosine deaminase inhibitor
Product Description
1-Deazaadenosine is an inhibitor of adenosine deaminase (Ki = 0.66 μM). Demonstrates antitumor activity in a range of leukemia cell lines.Product Specifications
Molecular Weight
266.25
Formula
C11H14N4O4
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
3-β-D-Ribofuranosyl-3H-imidazo[4,5-b]pyridin-7-amine
CAS Number
14432-09-8
PubChem ID
159738
InChI Key
NVUDDRWKCUAERS-PNHWDRBUSA-N
SMILES
NC1=C2C(N([C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)C=N2)=NC=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 6.66 | 25 |
Preparing Stock Solutions
for 1-Deazaadenosine
The following data is based on the product molecular weight 266.25
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.25 mM | 15.02 mL | 75.12 mL | 150.23 mL |
| 1.25 mM | 3.00 mL | 15.02 mL | 30.05 mL |
| 2.5 mM | 1.50 mL | 7.51 mL | 15.02 mL |
| 12.5 mM | 0.30 mL | 1.50 mL | 3.00 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Cristalli Improved synthesis and antitumor activity of 1-deazaadenosine. J.Med.Chem. 1987 PMID: 3625714
- Cristalli Adenosine deaminase inhibitors: Structure-activity relationships in 1-deazaadenosine and erythro-9-(2-hydroxy-3-nonyl)adenine analogues. Drug Dev.Res.
Product Specific Notices for 1-Deazaadenosine
For research use only
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