Simple Plex Discovery Control for Human TRANCE/RANK L

Name: Simple Plex Discovery Control for Human TRANCE/RANK L
Brand: ProteinSimple
SKU: 897972

ProteinSimple, part of Bio-Techne | Catalog # 897972

Product Datasheet / COA

Control for use with Human TRANCE/RANK L/TNFSF11 Simple Plex Assay Cartridge Kit

Summary for Simple Plex Discovery Control for Human TRANCE/RANK L

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human TRANCE/RANK L/TNFSF11 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

TRANCE (TNF-related activation-induced cytokines), also known as RANK Ligand, OPGL, or ODF, is a TNF superfamily ligand produced by osteoblasts, bone marrow stromal cells, and activated T cells. It signals through RANK and is antagonized by the decoy receptor Osteoprotegerin. TRANCE stimulates bone resorption, is required for osteoclast differentiation, and is associated with the development of osteoporosis, vascular calcification, osteopetrosis, and progestin-induced breast cancer. It also mediates body temperature regulation and is essential for the development of a lactating mammary gland.

Product Specifications for Simple Plex Discovery Control for Human TRANCE/RANK L

Species

Human

Preparation & Storage

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Background: TRANCE/TNFSF11/RANK L

Item	Value
Long Name	TNF-related Activation-induced Cytokine
Entrez Gene IDs	8600 (Human); 21943 (Mouse); 117516 (Rat); 102137946 (Cynomolgus Monkey)
Alternate Names	CD254, CD254 antigen, ODF, OPGL, OPGLOPTB2, Osteoclast differentiation factor, Osteoprotegerin ligand, RANK L, RANKL, RANKLreceptor activator of nuclear factor kappa B ligand, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TNFSF11, TRANCE, TRANCEODFhRANKL2, sOdf, tumor necrosis factor (ligand) superfamily, member 11, tumor necrosis factor ligand superfamily member 11

Product Documents for Simple Plex Discovery Control for Human TRANCE/RANK L

Product Datasheets

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