Simple Plex Discovery Control for Human Galectin-9
ProteinSimple, part of Bio-Techne | Catalog # 897156
Control for use with Discovery Human Galectin-9 Simple Plex Assay Cartridge Kit
Key Product Details
Species
Human
Product Summary for Simple Plex Discovery Control for Human Galectin-9
INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human Galectin-9 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.”
Formulation, Preparation, and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: Galectin-9
Galectin-9 is a secreted carbohydrate-binding protein with two lectin domains connected by a linker region. Progressive deletion within the linker region generates an isoform known as Ecalectin or UAT. Galectin-9 binds to carbohydrate moieties of IgE, preventing immune complex formation, mast cell degranulation, and asthmatic and cutaneous anaphylaxis reactions. It functions as an eosinophil chemoattractant and induces the maturation of dendritic cells which promote Th1 polarization. Galectin-9 binds to TIM-3, inhibiting Th1 cell and CD8+ T cell responses but promoting Treg differentiation and activity. Galectin-9 suppresses tumor cell metastasis by interfering with the associations between hyaluronic acid and CD44 and between VCAM-1 and Integrin alpha4 beta1. The Ecalectin isoform (UAT; urate transporter) can be expressed as an integral membrane protein and mediate the cellular efflux of urate.
Alternate Names
Ecalectin, GAL9, Galectin9, LGALS9
Gene Symbol
LGALS9
Additional Galectin-9 Products
Product Documents for Simple Plex Discovery Control for Human Galectin-9
Product Specific Notices for Simple Plex Discovery Control for Human Galectin-9
For research use only
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