Simple Plex Discovery Control for Human Coagulation Fac III
ProteinSimple, part of Bio-Techne | Catalog # 897216
Control for use with Discovery Human Coagulation Factor III/Tissue Factor Simple Plex Assay Cartridge Kit
Key Product Details
Species
Human
Product Summary for Simple Plex Discovery Control for Human Coagulation Fac III
INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human Coagulation Factor III/Tissue Factor concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information
Formulation, Preparation, and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: Coagulation Factor III/Tissue Factor
Coagulation Factor III, also known as Tissue Factor (TF), Thromboplastin, and CD142, is the primary initiator of the extrinsic coagulation pathway. It is a transmembrane protein that is consitutively expressed in subendothelial cells throughout the vasculature and is inducible on endothelial cells and monocytes. Damage to the vessel wall exposes Coagulation Factor III to circulating Factor VII, triggering the proteolytic cascade that results in fibrin clot formation. Coagulation Factor III plays an important role in thrombotic diseases, disseminated intravascular coagulation, and atherosclerosis. It also plays a role in non-hemostatic inflammation, angiogenesis, and tumor progression.
Alternate Names
CD142, F3, Thromboplastin, Tissue Factor
Gene Symbol
F3
Additional Coagulation Factor III/Tissue Factor Products
Product Documents for Simple Plex Discovery Control for Human Coagulation Fac III
Product Specific Notices for Simple Plex Discovery Control for Human Coagulation Fac III
For research use only
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