INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human Proprotein Convertase 9/PCSK9 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

This family of serine proteases consists of furin and proprotein convertases encoded by PCSK genes. They are important in a variety of processes. Furin has an essential role in embryogenesis and homeostasis and is implicated in various pathologies such as cancer, neurodegenerative diseases and anthrax. Mutations in the PC1/PCSK1 gene are associated with obesity and impaired prohormone processing.

Product Specifications for Simple Plex Control for Human Proprotein Convertase 9/PCSK9

Species	Human
Applications	Control, Simple Plex Automated Immunoassay
Source	N/A

Preparation & Storage

Shipping Conditions

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Background: Proprotein Convertase 9/PCSK9

Item	Value
Entrez Gene IDs	255738 (Human); 100102 (Mouse); 298296 (Rat); 102142788 (Cynomolgus Monkey)
Alternate Names	EC 3.4.21, EC 3.4.21.111, FH3, FH3neural apoptosis regulated convertase 1, FHCL3, HCHOLA3, LDLCQ1, NARC-1, NARC-1convertase subtilisin/kexin type 9 preproprotein, NARC1, NARC1EC 3.4.21.-, Neural apoptosis-regulated convertase 1, PC9, PCSK9, Proprotein Convertase 9, Subtilisin/kexin-like protease PC9, hypercholesterolemia, autosomal dominant 3, proprotein convertase subtilisin/kexin type 9

Product Documents for Simple Plex Control for Human Proprotein Convertase 9/PCSK9

Product Datasheets

Download Product Datasheets

Simple Plex Control for Human Proprotein Convertase 9/PCSK9

ProteinSimple, part of Bio-Techne | Catalog # 898101

Key Product Details

Summary for Simple Plex Control for Human Proprotein Convertase 9/PCSK9

Product Specifications for Simple Plex Control for Human Proprotein Convertase 9/PCSK9

Preparation & Storage

Background: Proprotein Convertase 9/PCSK9

Product Documents for Simple Plex Control for Human Proprotein Convertase 9/PCSK9

Product Datasheets

COA

Certificate of Analysis

CONTACT INFORMATION

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