Simple Plex Control for Human HGFR/c-MET
ProteinSimple, part of Bio-Techne | Catalog # 898327
Control for use with Human HGFR/c-MET Simple Plex Cartridge Kit
Key Product Details
Species
Human
Applications
Control, Simple Plex Automated Immunoassay
Product Summary for Simple Plex Control for Human HGFR/c-MET
INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human HGFR/c-MET concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.
Formulation, Preparation, and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: HGFR/c-MET
HGFR (Hepatocyte Growth Factor Receptor), also known as Met, is a receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. In the absence of ligand, HGFR forms noncovalent complexes with a variety of membrane proteins including CD44v6, CD151, EGFR, Fas, Integrin alpha 6 beta 4, Plexins B1, 2, 3, and MSPR/Ron. Ligation of one complex component triggers activation of the other, followed by cooperative signaling effects. Formation of some of these heteromeric complexes is a requirement for epithelial cell morphogenesis and tumor cell invasion. Paracrine induction of epithelial cell scattering and branching tubulogenesis results from the stimulation of HGFR on undifferentiated epithelium by HGF released from neighboring mesenchymal cells.
Long Name
Hepatocyte Growth Factor Receptor
Alternate Names
c-MET, cMET, HGF R, MET
Gene Symbol
MET
Additional HGFR/c-MET Products
Product Documents for Simple Plex Control for Human HGFR/c-MET
Product Specific Notices for Simple Plex Control for Human HGFR/c-MET
For research use only
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