Non-Human Primate IL-8/CXCL8 Cartridge
ProteinSimple, part of Bio-Techne | Catalog # SPCKB-NP-011309
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Key Product Details
Assay Length
Sample Type & Volume Required Per Well*
Sensitivity
Assay Range
Non-Human Primate IL-8/CXCL8 Cartridge Summary
*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay's minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.
Compatible Instruments
Ella Automated Immunoassay System
Product Specifications
Assay Type
Format
Reactivity
Specificity
Cross-reactivity
Interference
Precision
Intra-Assay Precision (Precision within an assay) Each control was tested 16 times in one assay.
Inter-Assay Precision (Precision between assays) Replicates of each control were tested in multiple assays performed by at least three technicians using two lots of reagents.
Cell Culture Supernates, EDTA Plasma, Heparin Plasma, Serum
| Intra-Assay Precision | Inter-Assay Precision | |||
|---|---|---|---|---|
| Sample | 1 | 2 | 1 | 2 |
| n | 16 | 16 | 10 | 10 |
| Mean (pg/mL) | 28.7 | 1362 | 27.3 | 1463 |
| Standard Deviation | 1.41 | 89.8 | 1.41 | 125 |
| CV% | 4.9 | 6.6 | 5.2 | 8.6 |
Recovery for Non-Human Primate IL-8/CXCL8 Cartridge
Recovery was not necessary as IL-8 shows 5 points of natural linearity.
Linearity
Samples containing and/or spiked with high concentrations of IL-8 were serially diluted with Sample Diluent to produce samples within the dynamic range of the assay.
Scientific Data Images for Non-Human Primate IL-8/CXCL8 Cartridge
Non-Human Primate IL-8 Ella Assay Standard Curve
Preparation and Storage
Shipping
Stability & Storage
Background: IL-8/CXCL8
Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.
Long Name
Alternate Names
Gene Symbol
Additional IL-8/CXCL8 Products
Product Documents for Non-Human Primate IL-8/CXCL8 Cartridge
Product Specific Notices for Non-Human Primate IL-8/CXCL8 Cartridge
For research use only