Non-Human Primate IL-17/IL17A Cartridge
ProteinSimple, part of Bio-Techne | Catalog # SPCKB-NP-011319
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Key Product Details
Assay Length
Sample Type & Volume Required Per Well*
Sensitivity
Assay Range
Non-Human Primate IL-17/IL17A Cartridge Summary
*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay's minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.
Compatible Instruments
Ella Automated Immunoassay System
Product Specifications
Assay Type
Format
Reactivity
Specificity
Cross-reactivity
Interference
Precision
Intra-Assay Precision (Precision within an assay) Each control was tested 16 times in one assay.
Inter-Assay Precision (Precision between assays) Replicates of each control were tested in multiple assays performed by at least three technicians using two lots of reagents.
Cell Culture Supernates, EDTA Plasma, Heparin Plasma, Serum
| Intra-Assay Precision | Inter-Assay Precision | |||
|---|---|---|---|---|
| Sample | 1 | 2 | 1 | 2 |
| n | 16 | 16 | 11 | 10 |
| Mean (pg/mL) | 57.7 | 2715 | 58.0 | 2513 |
| Standard Deviation | 2.80 | 108 | 3.38 | 188 |
| CV% | 4.9 | 4.0 | 5.8 | 7.5 |
Recovery for Non-Human Primate IL-17/IL17A Cartridge
Recovery at three different spiked concentrations within the range of the assay was evaluated.
| Sample Type | Average % Recovery | Range % |
|---|---|---|
| EDTA Plasma (n=4) | 99 | 99-101 |
| Heparin Plasma (n=4) | 102 | 90-120 |
| Serum (n=5) | 111 | 104-129 |
Linearity
Samples containing and/or spiked with high concentrations of IL-17A were serially diluted with Sample Diluent to produce samples within the dynamic range of the assay.
Scientific Data Images for Non-Human Primate IL-17/IL17A Cartridge
Non-Human Primate IL-17a Ella Assay Standard Curve
Preparation and Storage
Shipping
Stability & Storage
Background: IL-17/IL-17A
IL-17/IL-17A is a homodimeric cytokine that is secreted by IL-23 activated Th17 and Tc17 cells. It is upregulated during inflammation and contributes to disease severity by enhancing neutrophil infiltration and the production of pro-inflammatory chemokines. IL-17A can additionally form bioactive heterodimers with IL-17F. IL-17A and the IL-17A/F heterodimer signal through widely expressed receptor complexes containing IL-17 RA and IL-17 RC.
Long Name
Alternate Names
Entrez Gene IDs
Gene Symbol
Additional IL-17/IL-17A Products
Product Documents for Non-Human Primate IL-17/IL17A Cartridge
Product Specific Notices for Non-Human Primate IL-17/IL17A Cartridge
For research use only