SMARCAD1 Recombinant Enzymes

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-48883

Novus Biologicals, part of Bio-Techne
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NBP3-48883
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Key Product Details

Source

Sf 9 (baculovirus)

Conjugate

Unconjugated

View all SMARCAD1 Proteins and Enzymes »

Product Specifications

Description

Human SMRCD (aa 2-1027) fused to 6xHis and FLAG-tag at the N-terminus. (Uniprot: Q9H4L7-2)

Purity

Immunogen affinity purified

Protein / Peptide Type

Recombinant Enzymes

Formulation, Preparation and Storage

NBP3-48883
Formulation 20 mM Tris-HCl, pH 7.9, 150 mM NaCl, 15% glycerol, 2 mM MgCl2, 0.2 mM EDTA, 1 mM DTT, 10 mM beta-glycerophospate, 0.4 mM PMSF, 1 mM benzamidine and 0.4 mg/ml recombinant human insulin
Preservative No Preservative
Concentration Please see the vial label for concentration. If unlisted please contact technical services.
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -80C. Avoid freeze-thaw cycles.

Background: SMARCAD1

The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. SMARCAD1/ETL1 is a unique member of this family in that it contains two DEAD/H box motifs, and thus is also a member of the DEAD/H-box-containing helicase superfamily. The chromosomal position of SMARCAD1 has been mapped, and it resides in a region rich in breakpoints and deletions associated with several human diseases. It is suggested to play a role in genetic instability and development.

Alternate Names

ATP-dependent helicase 1, DKFZP762K2015, EC 3.6.1, EC 3.6.4.12, HEL1, hHEL1, KIAA1122ETL1DKFZp762K2015, subfamily a, containing DEAD/H box 1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A containing DEAD/H box 1, SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin

Gene Symbol

SMARCAD1

Additional SMARCAD1 Products

Product Documents for SMARCAD1 Recombinant Enzymes

Product Datasheets

Certificate of Analysis

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Product Specific Notices for SMARCAD1 Recombinant Enzymes

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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