Recombinant Human SIRT6 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBC1-18433

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NBC1-18433
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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all SIRT6 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-355 of Human SIRT6

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSVNYAAGLS PYADKGKCGL PEIFDPPEEL ERKVWELARL VWQSSSVVFH TGAGISTASG IPDFRGPHGV WTMEERGLAP KFDTTFESAR PTQTHMALVQ LERVGLLRFL VSQNVDGLHV RSGFPRDKLA ELHGNMFVEE CAKCKTQYVR DTVVGTMGLK ATGRLCTVAK ARGLRACRGE LRDTILDWED SLPDRDLALA DEASRNADLS ITLGTSLQIR PSGNLPLATK RRGGRLVIVN LQPTKHDRHA DLRIHGYVDE VMTRLMKHLG LEIPAWDGPR VLERALPPLP RPPTPKLEPK EESPTRINGS IPAGPKQEPC AQHNGSEPAS PKRERPTSPA PHRPPKRVKA KAVPS

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

41 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human SIRT6 His Protein

SDS-PAGE: Recombinant Human SIRT6 His Protein [NBC1-18433]

SDS-PAGE: Recombinant Human SIRT6 His Protein [NBC1-18433]

SDS-Page: SIRT6 Protein [NBC1-18433] - SIRT6, 41 kDa (375 aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

Formulation, Preparation and Storage

NBC1-18433
Formulation 20 mM Tris-HCl buffer (pH 7.5), 20% glycerol, 1 mM DTT, 0.1 M NaCl, 0.1 mM PMSF
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SIRT6

The SIRT6 is included in class IV of the sirtuin family, homologs to the yeast Sir2 protein. The functions of human sirtuins have not yet been determined; however, in yeast sirtuins are known to regulate epigenetic gene silencing. Also SIRT6, a chromatin-associated protein, appears to be involved in DNA repair. Recombinant SIRT6, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography techniques.

Long Name

NAD-dependent protein deacylase sirtuin-6

Alternate Names

EC 2.3.1.286, hSIRT6, SIR2-like protein 6, SIR2L6

Gene Symbol

SIRT6

Additional SIRT6 Products

Product Documents for Recombinant Human SIRT6 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human SIRT6 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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