Recombinant Human TIMP-2 Western Blot Standard Protein
R&D Systems, part of Bio-Techne | Catalog # WBC023
Key Product Details
- R&D Systems CHO-derived Recombinant Human TIMP-2 Western Blot Standard Protein (WBC023)
- Quality control testing to verify active proteins with lot specific assays by in-house scientists
- All R&D Systems proteins are covered with a 100% guarantee
Source
CHO
Conjugate
Unconjugated
Applications
Western Blot
Formulation, Preparation and Storage
WBC023
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
Background: TIMP-2
TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.
Long Name
Tissue Inhibitors of Metalloproteinases 2
Alternate Names
TIMP2
Gene Symbol
TIMP2
Additional TIMP-2 Products
Product Documents for Recombinant Human TIMP-2 Western Blot Standard Protein
Product Specific Notices for Recombinant Human TIMP-2 Western Blot Standard Protein
For research use only
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