Recombinant Human Mcl-1 Western Blot Standard Protein
R&D Systems, part of Bio-Techne | Catalog # WBC003
Key Product Details
- R&D Systems E. coli-derived Recombinant Human Mcl-1 Western Blot Standard Protein (WBC003)
- Quality control testing to verify active proteins with lot specific assays by in-house scientists
- All R&D Systems proteins are covered with a 100% guarantee
Source
Conjugate
Applications
Formulation, Preparation and Storage
WBC003
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date. |
Background: Mcl-1
Mcl-1 (Myeloid Cell Leukemia 1) is a member of the Bcl-2 family of proteins. Alternative splicing results in two distinct isoforms: Mcl-1L (long) enhances cell survival by inhibiting apoptosis, while Mcl-1S (short) promotes apoptosis. The elimination of Mcl-1L is an early and required step for DNA damage-induced apoptosis. Degradation of Mcl-1L is regulated by polyubiquitination, which targets Mcl-1L to the proteasome pathway.
Long Name
Alternate Names
Gene Symbol
Additional Mcl-1 Products
Product Documents for Recombinant Human Mcl-1 Western Blot Standard Protein
Product Specific Notices for Recombinant Human Mcl-1 Western Blot Standard Protein
For research use only