Recombinant Human RBM17 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-23445

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Key Product Details

Source

E. coli

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all RBM17 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-401 of Human RBM17

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSLYDDLGVE TSDSKTEGWS KNFKLLQSQL QVKKAALTQA KSQRTKQSTV LAPVIDLKRG GSSDDRQIVD TPPHVAAGLK DPVPSGFSAG EVLIPLADEY DPMFPNDYEK VVKRQREERQ RQRELERQKE IEEREKRRKD RHEASGFARR PDPDSDEDED YERERRKRSM GGAAIAPPTS LVEKDKELPR DFPYEEDSRP RSQSSKAAIP PPVYEEQDRP RSPTGPSNSF LANMGGTVAH KIMQKYGFRE GQGLGKHEQG LSTALSVEKT SKRGGKIIVG DATEKDASKK SDSNPLTEIL KCPTKVVLLR NMVGAGEVDE DLEVETKEEC EKYGKVGKCV IFEIPGAPDD EAVRIFLEFE RVESAIKAVV DLNGRYFGGR VVKACFYNLD KFRVLDLAEQ V

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

47.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human RBM17 His Protein

SDS-PAGE: Recombinant Human RBM17 His Protein [NBP2-23445]

SDS-PAGE: Recombinant Human RBM17 His Protein [NBP2-23445]

SDS-Page: RBM17 Protein [NBP2-23445]

Formulation, Preparation and Storage

NBP2-23445
Formulation 20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl, 10% glycerol, 1 mM DTT
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RBM17

RNA binding motif protein 17, also known as RBM17, is splice factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. This protein is involved in the regulation of alternative splicing and the utilization of cryptic splice sites. This protein promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia. Recombinant human RBM17 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

MGC14439, RNA binding motif protein 17, RNA-binding motif protein 17, SPF45DKFZp686F13131, splicing factor 45,45 kDa-splicing factor, splicing factor 45kDa

Gene Symbol

RBM17

Additional RBM17 Products

Product Documents for Recombinant Human RBM17 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human RBM17 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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