Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62452
Key Product Details
Source
Pichia pastoris
Conjugate
Unconjugated
Applications
Western Blot, ELISA
Product Specifications
Description
Recombinant dog interleukin-1RA.
Source:Pichia pastoris
Amino Acid Sequence:152 amino acid sequence of native canine IL-1RA.
Purity
>95%, by SDS-PAGE
Predicted Molecular Mass
17.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Protein / Peptide Type
Recombinant Protein
Scientific Data Images for Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein
![Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein ELISA: Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein [NBP2-62452] -](https://resources.bio-techne.com/images/products/nbp2-62452_recombinant-canine-il-1ra-il-1f3-il1rn-protein-2312025235980.jpg "ELISA: Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein [NBP2-62452] -")
ELISA: Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein [NBP2-62452] -
ELISA: Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein [NBP2-62452] - Dog Interleukin-1RA ELISARecombinant Dog interleukin-1RA detected using Goat anti Dog interleukin-1RA as the capture reagent and Goat anti Dog interleukin-1RA:Biotin as the detection reagent followed by Streptavidin:HRP
Formulation, Preparation and Storage
NBP2-62452
| Preparation Method | Recombinant protein expressed in Pichia pastoris and purified by ion-exchange chromatography. |
| Formulation | PBS |
| Preservative | 10% Trehalose |
| Concentration | Lyoph |
| Reconstitution | Reconstitute with 20 ul sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix vial after reconstitution. |
| Shipping | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store at -20C. Avoid freeze-thaw cycles. |
Background: IL-1ra/IL-1F3
IL-1ra (IL-1 receptor antagonist) is a widely expressed acute phase protein that serves to dampen inflammation. IL-1ra binds to both IL-1 RI and IL-1 RII. It competitively inhibits IL-1 (alpha or beta) binding to IL-1 RI and does not trigger recruitment of the accessory molecule IL-1 R AcP or activation of IL-1 RI signaling. IL-1ra blocks the proinflammatory actions of IL-1 including Prostaglandin E2 and IL-6 release from endothelial cells, fever generation, thrombocytosis, the production of hepatic acute phase proteins, and neutrophil expansion and infiltration.
Long Name
Interleukin 1 Receptor Antagonist
Alternate Names
DIRA, ICIL-1ra, IL-1F3, IL-1ra3, IL-1RN, IL1ra, IL1RN, MVCD4
Gene Symbol
IL1RN
Additional IL-1ra/IL-1F3 Products
Product Documents for Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein
Product Specific Notices for Recombinant Canine IL-1ra/IL-1F3/IL1RN Protein
This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.
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