CELT-133
Tocris Bioscience, part of Bio-Techne | Catalog # 7952
Selective hα1A adrenergic receptor fluorescent antagonist
Key Product Details
Description
Selective hα1A adrenergic receptor fluorescent antagonist
Product Description
CELT-133 is a selective hα1A adrenergic receptor fluorescent antagonist. It shows full selectivity for α1A over α2A (Ki= 5 nM and 15% of displacement at 1 μM respectively in radioligand binding assay). CELT-133 binds equally to all subtypes of α1 adrenergic receptor. Excitation and emission maxima (λ) are 560 and 571 nm, respectively. Wavelengths are compatible with use as an acceptor dye in TR-FRET assays, together with the CoraFluor™ 1 (Cat. No. 7920) TR-FRET donor.Add 76 μL of assay buffer containing 1% of DMSO to obtain a 100 μM stock solution, and use 250 nM as a working concentration.
Licensing Information
Sold under license from Celtarys ResearchOptical Data
| Emission Color | Yellow |
| λabs | 560 nm |
| λem | 571 nm |
| Application | Fluorescence polarization, Confocal microscopy, High content screening |
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Product Specifications
Molecular Weight
1318.43
Storage
Store at -20°C
Purity
≥95% (HPLC)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Background References
References are publications that support the biological activity of the product.
Product Specific Notices for CELT-133
For research use only
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