Key Product Details
| Description: | Pan RAS Tracer |
| Chemical Name: | N-(15-(5,5-Difluoro-7-(1H-pyrrol-2-yl)-5H-5λ4,6λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-13-oxo-3,6,9-trioxa-12-azapentadecyl)-5-(2-((6-((((3-(6-hydroxy-3-oxoisoindolin-1-yl)-1H-indol-2-yl)methyl)amino)methyl)-1H-indol-1-yl)methyl)-1H-imidazol-1-yl)pentanamide |
| Purity: | ≥95% (HPLC) |
| Molecular Weight: | 1088.04 |
Biological Activity for BI 2852 FL
BI 2852 FL is a cell-permeable pan-RAS bioluminescence resonance energy transfer (BRET) fluorescent probe. BI 2852 FL is synthesized by conjugating a fluorophore to a derivative of the reversible SI/II-P KRAS inhibitor, BI 2852. BI 2852 FL is used in competitive BRET format to quantify SII-P engagement to multimeric RAS complexes in live cells.
Optical Data for BI 2852 FL
| λabs | 495 nm |
|---|---|
| λem | 520 nm |
Plan Your Experiments
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