Mouse Plexin A1 (NP_032907) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC0982
Key Product Details
Species
Mouse
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Plexin A1
Plexin A1 is a 200 kDa type I transmembrane member of the Plexin family of Semaphorin signal transducers. It consists of a 1218 amino acid (aa) extracellular domain with one Sema domain, a spacer, and four tandem IPT/TIG domains, a 21 aa transmembrane segment, and a 631 aa cytoplasmic domain. Plexin A1 binds the transmembrane Semaphorin 6D directly and binds the Class 3 secreted Semaphorins indirectly via Neuropilin-1 and -2. It mediates cytoskeletal remodeling that results in cell migration and axon repulsion. Within aa 964 - 1152 (in the IPT/TIG region), human Plexin A1 shares 93% aa sequence identity with mouse and rat Plexin A1.
Alternate Names
NOVP, PLXN1, PLXNA1
Gene Symbol
PLXNA1
UniProt
Additional Plexin A1 Products
Product Documents for Mouse Plexin A1 (NP_032907) VersaClone cDNA
Product Specific Notices for Mouse Plexin A1 (NP_032907) VersaClone cDNA
For research use only
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