Mouse CD40 Ligand/TNFSF5 (NP_035746) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1395
Key Product Details
Species
Mouse
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: CD40 Ligand/TNFSF5
CD40 Ligand, also known as TNFSF5, CD154, TRAP, and gp39, is a trimeric protein that is expressed in transmembrane and soluble forms. It is expressed by many immune cell types as well as by endothelial and smooth muscle cells of the vasculature. It binds to CD40 on antigen presenting cells, platelets, and endothelial and epithelial cells, leading to enhanced B cell activation and T cell dependent humoral immune responses. CD40 Ligand dysregulation contributes to immune pathology in AIDS, atherosclerosis, atherothrombosis, and restenosis.
Alternate Names
CD154, CD40L, CD40LG, gp39, TNFSF5, TRAP
Gene Symbol
CD40LG
UniProt
Additional CD40 Ligand/TNFSF5 Products
Product Documents for Mouse CD40 Ligand/TNFSF5 (NP_035746) VersaClone cDNA
Product Specific Notices for Mouse CD40 Ligand/TNFSF5 (NP_035746) VersaClone cDNA
For research use only
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