Mouse BMP-3b/GDF-10 (AAB46753.1) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC3543
Key Product Details
Species
Mouse
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: BMP-3b/GDF-10
BMP-3b, also known as GDF-10, belongs to the TGF-beta superfamily. TGF-beta family proteins are synthesized and secreted as homodimeric or heterodimeric prepropeptides that are cleaved by proprotein convertases such as furin to generate the carboxy-terminal mature dimeric protein. BMP-3b is expressed in developing skeletal structures of the craniofacial region and the vertebral column as well as in the adult trachea, aorta, cerebellum, and uterus. BMP-3b promotes osteoblast generation and inhibits osteoclast differentiation. It is also upregulated in adipocytes during obesity where it inhibits adipogenesis and protects against high fat diet-induced obesity.
Long Name
Bone Morphogenetic Protein 3b
Alternate Names
BMP3b, GDF-10, GDF10
Gene Symbol
GDF10
UniProt
Additional BMP-3b/GDF-10 Products
Product Documents for Mouse BMP-3b/GDF-10 (AAB46753.1) VersaClone cDNA
Product Specific Notices for Mouse BMP-3b/GDF-10 (AAB46753.1) VersaClone cDNA
For research use only
Loading...
Loading...
Loading...