Mouse ACE/CD143 (NP_997507.1) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC3498
Key Product Details
Species
Mouse
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: ACE/CD143
ACE and ACE-2, two cell surface proteases, are important regulators of the renin-angiotensin system (RAS), which plays a key role in maintaining blood pressure homeostasis and fluid salt balance in mammals. Because of its location and specificity, ACE plays additional roles in immunity, reproduction and neuropeptide regulation. ACE exists in two isoforms. Somatic ACE comprises two highly similar protease domains whereas germinal ACE comprises a single protease domain. ACE-2 consists of a single protease domain and is an essential regulator of heart and lung function. It is also a cellular receptor for the Spike protein of SARS coronavirus that causes severe acute respiratory syndrome.
Long Name
Angiotensin I Converting Enzyme
Alternate Names
CD143, DCP1, Kininase II
Gene Symbol
ACE
UniProt
Additional ACE/CD143 Products
Product Documents for Mouse ACE/CD143 (NP_997507.1) VersaClone cDNA
Product Specific Notices for Mouse ACE/CD143 (NP_997507.1) VersaClone cDNA
For research use only
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