Human Tyk2 (NP_003322.3) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC3610
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Tyk2
Tyk2 belongs to the Janus family of intracellular tyrosine kinases that are activated by receptors for many cytokines. Activation of Tyk2 occurs via phosphorylation at two adjacent tyrosine residues within the kinase domain. Tyk2 is required for interferon-mediated tyrosine phosphorylation of STAT3 and interferon a receptor 1. Mice lacking Tyk2 are susceptible to parasitic infection but resistant to autoimmune arthritis.
Long Name
Protein tyrosine kinase 2
Alternate Names
EC 2.7.10, EC 2.7.10.2, JTK1, non-receptor tyrosine-protein kinase TYK2, tyrosine kinase 2
Gene Symbol
TYK2
UniProt
Additional Tyk2 Products
Product Documents for Human Tyk2 (NP_003322.3) VersaClone cDNA
Product Specific Notices for Human Tyk2 (NP_003322.3) VersaClone cDNA
For research use only
Loading...
Loading...
Loading...