Human PDGF-B (NP_002599.1) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC3286
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: PDGF-B
Platelet-derived growth factor-B (PDGF-B) is a cytokine that can form disulfide-linked homodimers or heterodimers with PDGF-A. These proteins regulate diverse cellular functions by binding to and inducing the homo- or hetero-dimerization of PDGF R alpha and R beta. PDGF-AB binds to alpha receptor homodimers and the heterodimeric receptor, while PDGF-BB additionally binds to beta receptor homodimers. PDGF-AA and -AB promote cell proliferation, cell survival, cytoskeletal rearrangement, cell migration and extracellular matrix production. They are important for the development of oligodendrocytes, testicular Leydig cells, alveolar smooth muscle cells, hair follicles, and intestinal villus.
Long Name
Platelet-derived Growth Factor B
Alternate Names
C-Sis, IBGC5, PDGF-2, PDGF2, PDGFB, SIS, SSV
Gene Symbol
PDGFB
UniProt
Additional PDGF-B Products
Product Documents for Human PDGF-B (NP_002599.1) VersaClone cDNA
Product Specific Notices for Human PDGF-B (NP_002599.1) VersaClone cDNA
For research use only
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