Human PADI2 (NP_031391.2) VersaClone cDNA

R&D Systems, part of Bio-Techne | Catalog # RDC3572

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Key Product Details

Species

Human

Accession Number

NP_031391.2

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: PADI2

PADI2 / PAD2 is a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. Each family member has a distinct substrate specificity and tissue expression pattern. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative disorders, including Alzheimers disease and multiple sclerosis, and it has also been implicated in the pathogenesis of glaucoma.

Long Name

Peptidyl Arginine Deiminase type II

Alternate Names

PAD-H19, PAD2, PDI2, Peptidylarginine Deiminase II

Entrez Gene IDs

11240 (Human); 18600 (Mouse); 29511 (Rat)

Gene Symbol

PADI2

UniProt

NP_031391.2 (Human)

Additional PADI2 Products

Product Documents for Human PADI2 (NP_031391.2) VersaClone cDNA

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Human PADI2 (NP_031391.2) VersaClone cDNA

For research use only

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