Human NKG2A/CD159a (NP_002250) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC2583
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: NKG2A/CD159a
NKG2A and NKG2C are type II transmembrane proteins with extracellular C-type lectin domains. These proteins heterodimerize with CD94 to form complexes that recognize HLA-E as ligand. The NKG2A/CD94 complex delivers an inhibitory signal resulting from ITIMs within the NKG2A cytoplasmic domain. NKG2C/CD94 provides an activating signal due to association with the ITAM-containing DAP12 adapter protein. These complexes are expressed on NK and T cell subsets.
Long Name
Natural Killer G2A
Alternate Names
CD159a, Klrc1, NKG2
Gene Symbol
KLRC1
UniProt
Additional NKG2A/CD159a Products
Product Documents for Human NKG2A/CD159a (NP_002250) VersaClone cDNA
Product Specific Notices for Human NKG2A/CD159a (NP_002250) VersaClone cDNA
For research use only
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