Human JAM-C (NP_116190) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1620
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: JAM-C
Members of the junctional adhesion molecule (JAM) family are type I transmembrane glycoproteins of the immunoglobulin (Ig) superfamily that are localized in the tight junctions between endothelial or epithelial cells and appear to be involved in leukocyte transmigration. JAM-A, also known as platelet adhesion molecule 1 (PAM-1) and platelet F11 receptor, contains two V-type Ig-like domains, forms homodimers, and interacts with LFA-1. JAM-B (vasculoendothelial or VE-JAM) and JAM-C each contain two Ig domains (one V-type and one C2-type), a cytoplasmic PDZ-binding motif and a PKC phosphorylation site. JAM-C interacts with MAC-1 and facilitates JAM-B interaction with integrin alpha 4 beta 1.
Long Name
Junctional Adhesion Molecule C
Alternate Names
CD323, JAM3, JAMC
Gene Symbol
JAM3
UniProt
Additional JAM-C Products
Product Documents for Human JAM-C (NP_116190) VersaClone cDNA
Product Specific Notices for Human JAM-C (NP_116190) VersaClone cDNA
For research use only
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