Human IL-10 R alpha (NP_001549) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1290
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: IL-10 R alpha
Interleukin-10 Receptor alpha (IL-10 Ra), also known as IL-10 R1, is a transmembrane ligand-specific component of the IL-10 receptor complex. It associates with IL-10 R beta to mediate the effects of IL-10 in the control of microbial infections, allergic and autoimmune inflammation, and cancer. IL-10 R beta also associates with IL-20 R alpha, IL-22 R alpha, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29. Immunosuppressive signal transduction through the IL-10 receptor complex can be inhibited by activation of TLR2, 4, or 9, enabling strengthened immune responses during infection.
Long Name
Interleukin 10 Receptor alpha
Alternate Names
CDw210a, IL-10Ra, IL10R alpha, IL10RA
Gene Symbol
IL10RA
UniProt
Additional IL-10 R alpha Products
Product Documents for Human IL-10 R alpha (NP_001549) VersaClone cDNA
Product Specific Notices for Human IL-10 R alpha (NP_001549) VersaClone cDNA
For research use only
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