Human GLP-2R (NP_004237) VersaClone cDNA

R&D Systems, part of Bio-Techne | Catalog # RDC0295

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Key Product Details

Species

Human

Accession Number

NP_004237

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: GLP-2R

GLP2R, a Glucagon Receptor, is closely related to the Glucagon Receptor and to the GLP1 Receptor. The glucagon-like peptides (GLP-1 and GLP-2) are proglucagon-derived peptides cosecreted from gut endocrine cells in response to nutrient ingestion. The actions of GLP-2 are mediated by the GLP-2 receptor expressed on subsets of enteric nerves and enteroendocrine cells in the stomach and small and large intestine. Activation of GLP2R signaling promotes expansion of the mucosal epithelium indirectly via activation of growth and anti-apoptotic pathways. GLP2R, through its ligand glucagon-like peptide 2 (GLP2), has been shown to prevent intestinal hypoplasia resulting from total parenteral nutrition. GLP2R has been reported primarily in the gastrointestinal tract, including intestine and stomach. In rats, GLPR2 has been shown in brain and lung. An EST has been isolated from a lung cancer library.

Long Name

Glucagon-like Peptide 2 Receptor

Alternate Names

GLP2R

Entrez Gene IDs

9340 (Human); 93896 (Mouse); 60432 (Rat)

Gene Symbol

GLP2R

UniProt

NP_004237

Additional GLP-2R Products

Product Documents for Human GLP-2R (NP_004237) VersaClone cDNA

Product Datasheets

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Product Specific Notices for Human GLP-2R (NP_004237) VersaClone cDNA

For research use only

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