Human GDF-11/BMP-11 (NP_005802.1) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC3546
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: GDF-11/BMP-11
GDF-11 (Growth Differentiation Factor 11), also known as BMP-11, is closely related to GDF-8. It is widely expressed during development and plays a role in palate, vertebrae, tail, kidney, and olfactory neuron formation. GDF-11 signals through Activin type II receptors and induces phosphorylation of Smad2 to mediate axial patterning. Systemic GDF-11 levels decline with age, and administration of GDF-11 can reverse age-related cardiac hypertrophy, restore genomic integrity and muscle stem cell health, and enhance angiogenesis and neurogenesis.
Long Name
Growth Differentiation Factor 11
Alternate Names
BMP-11, BMP11, GDF11
Entrez Gene IDs
10220 (Human)
Gene Symbol
GDF11
UniProt
Additional GDF-11/BMP-11 Products
Product Documents for Human GDF-11/BMP-11 (NP_005802.1) VersaClone cDNA
Product Specific Notices for Human GDF-11/BMP-11 (NP_005802.1) VersaClone cDNA
For research use only
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