Human CX3CL1/Fractalkine (NP_002987) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC2120
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: CX3CL1/Fractalkine
CX3CL1/Fractalkine is a transmembrane adhesion protein with a chemokine domain separated from the membrane by a mucin stalk. It is upregulated on many cell types during inflammation. The chemokine and mucin regions can be shed as a soluble chemokine that signals through the receptor CX3CR1. During extravasation, membrane-bound CX3CL1 traps leukocytes, then is cleaved to allow diapedesis. Soluble CX3CL1 protects neurons from microglial neurotoxicity, recruits macrophages for wound healing, recruits osteoclast precursors for bone resorption, and contributes to pathogenesis in coronary artery disease.
Alternate Names
FKN, Fractalkine, Neurotactin
Gene Symbol
CX3CL1
UniProt
Additional CX3CL1/Fractalkine Products
Product Documents for Human CX3CL1/Fractalkine (NP_002987) VersaClone cDNA
Product Specific Notices for Human CX3CL1/Fractalkine (NP_002987) VersaClone cDNA
For research use only
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