Human ALDH2 (NP_000681.2) VersaClone cDNA

R&D Systems, part of Bio-Techne | Catalog # RDC3323

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Key Product Details

Species

Human

Accession Number

NP_000681.2

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: ALDH2

ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq]

Long Name

Aldehyde Dehydrogenase 2 Family Member

Alternate Names

ALDHI, ALDM

Entrez Gene IDs

217 (Human); 11669 (Mouse)

Gene Symbol

ALDH2

UniProt

NP_000681.2 (Human)

Additional ALDH2 Products

Product Documents for Human ALDH2 (NP_000681.2) VersaClone cDNA

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Human ALDH2 (NP_000681.2) VersaClone cDNA

For research use only

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