Cynomolgus Monkey IL-27 p28 (EHH60284) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC2737
Key Product Details
Species
Cynomolgus Monkey
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: IL-27
IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells, and it signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12 induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.
Long Name
Interleukin 27
Alternate Names
IL27
Gene Symbol
IL27
UniProt
Additional IL-27 Products
Product Documents for Cynomolgus Monkey IL-27 p28 (EHH60284) VersaClone cDNA
Product Specific Notices for Cynomolgus Monkey IL-27 p28 (EHH60284) VersaClone cDNA
For research use only
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