uPAR Antibody (VIM5) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-09119

Novus Biologicals, part of Bio-Techne
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NBP3-09119
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # VIM5

Format

BSA Free

Concentration

1 mg/ml

View all uPAR Antibodies »

Product Specifications

Immunogen

human myeloid cell line THP-1

Specificity

The mouse monoclonal antibody VIM5 recognizes CD87 (urokinase plasminogen activator receptor), a 36-68 kDa single-chain GPI-anchored extracellular glycoprotein expressed on granulocytes, monocytes/macrophages, dendritic cells, endothelial cells, fibroblasts and keratinocytes.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for uPAR Antibody (VIM5) - BSA Free

Flow Cytometry: uPAR Antibody (VIM5) - BSA Free [NBP3-09119]

Flow Cytometry: uPAR Antibody (VIM5) - BSA Free [NBP3-09119]

Flow Cytometry: uPAR Antibody (VIM5) [NBP3-09119] - Analysis (surface staining) of human peripheral blood with anti-human CD87 (VIM5) purified, GAM-APC.

Applications for uPAR Antibody (VIM5) - BSA Free

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

Phosphate buffered saline (PBS), pH 7.4

Format

BSA Free

Preservative

15mM Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: uPAR

uPAR (Urokinase plasminogen activator receptor) is a glycoprotein I anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum beta globulin plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.

Long Name

Urokinase-type Plasminogen Activator Receptor

Alternate Names

PLAUR

Gene Symbol

PLAUR

Additional uPAR Products

Product Documents for uPAR Antibody (VIM5) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for uPAR Antibody (VIM5) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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