TGF-beta Antibody (TGFB/510) - Azide and BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08739
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human, Mouse, Rat, Bovine, Canine, Hamster, Monkey
Applications
ELISA, Functional Assay
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # TGFB/510
Format
Azide and BSA Free
Concentration
1 mg/ml
Product Specifications
Immunogen
Full length recombinant human TGF-beta protein
Localization
Cytoplasm and extracellular (secreted)
Specificity
This monoclonal antibody recognizes TGF beta 1, 2 and 3. TGFs inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells. Most breast lesions, benign and malignant, involve abnormal proliferation and altered architecture of stromal and/or epithelial elements.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Theoretical MW
13 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Description
1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP3-07708).
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
Applications for TGF-beta Antibody (TGFB/510) - Azide and BSA Free
Application
Recommended Usage
ELISA
0.1-0.4 ug/ml
Application Notes
Functional Assay: Order antibody without BSA/Azide
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
10 mM PBS
Format
Azide and BSA Free
Preservative
No Preservative
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Background: TGF-beta
TGF-beta 1 (Transforming Growth Factor beta 1) is a pleiotrophic cytokine that regulates immune function, proliferation, and epithelial-mesenchymal transition. TGF-beta 1 associates with LAP to form a latent complex. It can be is activated from latency by plasmin, matrix metalloproteases, thrombospondin 1, and a subset of integrins. TGF-beta 1 signals through complexes of TGF-beta RII with TGF-beta RI/ALK-5 or ALK-1. TGF-beta signaling is modulated by the accessory receptors TGF-beta RIII/Betaglycan and Endoglin/CD105.
Long Name
Transforming Growth Factor beta
Alternate Names
TGFbeta
Gene Symbol
TGFB1
Additional TGF-beta Products
Product Documents for TGF-beta Antibody (TGFB/510) - Azide and BSA Free
Product Specific Notices for TGF-beta Antibody (TGFB/510) - Azide and BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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