Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular head regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages. The serum concentration is 88 ng/ml in healthy individuals (2).

Long Name

Surfactant Pulmonary Associated Protein D

Alternate Names

Collectin 7, PSP-D, SFTP4, SFTPD, SPD

Gene Symbol

SFTPD

Additional SP-D Products

Product Documents for SP-D Antibody [FITC]

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Product Specific Notices for SP-D Antibody [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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SP-D Antibody [FITC]

Novus Biologicals, part of Bio-Techne | Catalog # AF6839F

Key Product Details

Species Reactivity

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Antibody Source

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Product Specifications

Immunogen

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Applications for SP-D Antibody [FITC]

Western Blot

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Background: SP-D