SARS-CoV-2 Spike S2 Subunit Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB11130
Recombinant Monoclonal Antibody.
Conjugate
Catalog #
Key Product Details
Species Reactivity
SARS-CoV-2
Applications
ELISA
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Rabbit IgG Clone # 2812B
Product Specifications
Immunogen
Recombinant SARS-CoV2 Spike S2 Subunit
Specificity
Detects SARS-CoV-2 Spike S2 Subunit in direct ELISAs.
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Applications for SARS-CoV-2 Spike S2 Subunit Antibody
Application
Recommended Usage
ELISA
This antibody functions as a SARS-CoV-2 Spike S2 Subunit ELISA detection antibody when paired with Catalog # MAB10850
Formulation, Preparation, and Storage
Purification
Protein A or G purified from cell culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Spike S2 Subunit
Spike S2 subunit contains the C-terminal region of the coronavirus Spike protein. It contains two heptad repeat domains, HR1 and HR2, that interact to form a six-helix bundle bringing the viral membrane close to the host cell membrane allowing fusion to occur. Inhibitors that block this process have therapeutic potential and are currently being studied. In addition to the heptad repeats, there is a C-terminal transmembrane domain responsible for anchoring the Spike protein in the viral membrane and a short cytoplasmic tail.
Long Name
Spike Protein, S2 Subunit
Alternate Names
COVID-19, S2 protein, SARS-CoV-2, SARS-CoV-2 Spike, Spike glycoprotein Subunit 2, spike protein, Spike protein S2, structural protein, surface glycoprotein
Additional Spike S2 Subunit Products
Product Documents for SARS-CoV-2 Spike S2 Subunit Antibody
Product Specific Notices for SARS-CoV-2 Spike S2 Subunit Antibody
For research use only
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