Proprotein Convertase 1/PCSK1 Antibody [DyLight 755]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98925IR
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human
Applications
ELISA
Label
DyLight 755 (Excitation = 754 nm, Emission = 776 nm)
Antibody Source
Polyclonal Rabbit IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Produced in rabbits immunized with purified, recombinant Human Proprotein Convertase 1/PCSK1 (Accession#: NP_000430.3; Met 1-Arg 617)
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Applications for Proprotein Convertase 1/PCSK1 Antibody [DyLight 755]
Application
Recommended Usage
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen and protein A Affinity-purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Proprotein Convertase 1/PCSK1
Proprotein Convertase 1, also known as PCSK1, PC1 or PC3, is a serine protease in the Furin family. Autocatalytic processing results in the removal of the pro peptide as well as a region from the C-terminus, which leads to the production of the most active 66 kDa form. PCSK1 is predominantly expressed in endocrine and neural cells and is stored in dense-core secretory vesicles, PCSK1 processes several endocrine and neural prohormones, including opiomelanocortin, somatostatin, enkephalin, insulin, dynorphin, and thyrotropin-releasing hormone. PCSK1 mutations are assiciated with obesity and impaired prohormone processing.
Alternate Names
NEC1, PCSK1
Gene Symbol
PCSK1
Additional Proprotein Convertase 1/PCSK1 Products
Product Documents for Proprotein Convertase 1/PCSK1 Antibody [DyLight 755]
Product Specific Notices for Proprotein Convertase 1/PCSK1 Antibody [DyLight 755]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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