Proprotein Convertase 1/PCSK1 Antibody - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13741
Key Product Details
Species Reactivity
Validated:
Human
Predicted:
Mouse (94%), Rat (96%). Backed by our 100% Guarantee.
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Format
BSA Free
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
This antibody was developed against a recombinant protein corresponding to the amino acids: RQFVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWN
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Description
Novus Biologicals Rabbit Proprotein Convertase 1/PCSK1 Antibody - BSA Free (NBP2-13741) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
Scientific Data Images for Proprotein Convertase 1/PCSK1 Antibody - BSA Free
![Immunohistochemistry-Paraffin: Proprotein Convertase 1/PCSK1 Antibody [NBP2-13741]](https://resources.bio-techne.com/images/products/PC1-3-Antibody-Immunohistochemistry-Paraffin-NBP2-13741-img0001.jpg "Immunohistochemistry-Paraffin: Proprotein Convertase 1/PCSK1 Antibody [NBP2-13741]")
Immunohistochemistry-Paraffin: Proprotein Convertase 1/PCSK1 Antibody [NBP2-13741]
Immunohistochemistry-Paraffin: PC1/3 Antibody [NBP2-13741] Staining of human liver shows strong cytoplasmic positivity in hepatocytes.Applications for Proprotein Convertase 1/PCSK1 Antibody - BSA Free
Application
Recommended Usage
Immunohistochemistry
1:200 - 1:500
Immunohistochemistry-Paraffin
1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Formulation, Preparation, and Storage
Purification
Immunogen affinity purified
Formulation
PBS (pH 7.2) and 40% Glycerol
Format
BSA Free
Preservative
0.02% Sodium Azide
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Proprotein Convertase 1/PCSK1
Proprotein Convertase 1, also known as PCSK1, PC1 or PC3, is a serine protease in the Furin family. Autocatalytic processing results in the removal of the pro peptide as well as a region from the C-terminus, which leads to the production of the most active 66 kDa form. PCSK1 is predominantly expressed in endocrine and neural cells and is stored in dense-core secretory vesicles, PCSK1 processes several endocrine and neural prohormones, including opiomelanocortin, somatostatin, enkephalin, insulin, dynorphin, and thyrotropin-releasing hormone. PCSK1 mutations are assiciated with obesity and impaired prohormone processing.
Alternate Names
NEC1, PCSK1
Gene Symbol
PCSK1
Additional Proprotein Convertase 1/PCSK1 Products
Product Documents for Proprotein Convertase 1/PCSK1 Antibody - BSA Free
Product Specific Notices for Proprotein Convertase 1/PCSK1 Antibody - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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