PP2C alpha/PPM1A Antibody (p6c7) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-04333

Novus Biologicals, part of Bio-Techne

Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # p6c7

Format

BSA Free

Concentration

1.0 mg/ml

View all PP2C alpha/PPM1A Antibodies »

Product Specifications

Immunogen

Recombinant human PP2C alpha/PPM1A (1-382aa) purified from E. coli (NP_066283).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Theoretical MW

42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Mouse PP2C alpha/PPM1A Antibody (p6c7) - BSA Free (NBP1-04333) is a monoclonal antibody validated for use in WB, ELISA and ICC/IF. Anti-PP2C alpha/PPM1A Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for PP2C alpha/PPM1A Antibody (p6c7) - BSA Free

Western Blot: PP2C alpha/PPM1A Antibody (p6c7)BSA Free [NBP1-04333]

Western Blot: PP2C alpha/PPM1A Antibody (p6c7)BSA Free [NBP1-04333]

PP2C-alpha-PPM1A-Antibody-p6c7-Western-Blot-NBP1-04333-img0003.jpg
Western Blot: PP2C alpha/PPM1A Antibody (p6c7)BSA Free [NBP1-04333]

Western Blot: PP2C alpha/PPM1A Antibody (p6c7)BSA Free [NBP1-04333]

Western Blot: PP2C alpha/PPM1A Antibody (p6c7) [NBP1-04333] - Mouse liver cytosol extract was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-PP2Calpha(1:250). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a DAP detection system. Arrow indicates PP2Calpha(~43kDa).

Applications for PP2C alpha/PPM1A Antibody (p6c7) - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1:250-1:1000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4), 10% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PP2C alpha/PPM1A

Protein phosphatase 2C(PP2Calpha) is a Mn2+- or Mg2+-dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNK MAPK pathways and regulates cellular stress response in eukaryotes. The PPM(metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2C, the prototypical member of the PPM family.

Long Name

Protein Phosphatase 2C alpha

Alternate Names

MMPa-2, MPPa-1, Pp2c1, PPM1A

Entrez Gene IDs

5494 (Human); 19042 (Mouse)

Gene Symbol

PPM1A

UniProt

P35813

Additional PP2C alpha/PPM1A Products

Product Documents for PP2C alpha/PPM1A Antibody (p6c7) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PP2C alpha/PPM1A Antibody (p6c7) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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