POLR1A Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-47093

Novus Biologicals, part of Bio-Techne
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NBP3-47093
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all POLR1A Antibodies »

Product Specifications

Immunogen

polymerase(RNA) I polypeptide A, 194kDa. (Uniprot# O95602)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit POLR1A Antibody - BSA Free (NBP3-47093) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for POLR1A Antibody - BSA Free

POLR1A Antibody - BSA Free

Western Blot: POLR1A Antibody - BSA Free [NBP3-47093] -

Western Blot: POLR1A Antibody - BSA Free [NBP3-47093] - HeLa cells were subjected to SDS PAGE followed by western blot with (POLR1A antibody) at dilution of 1:1000

Applications for POLR1A Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000
Application Notes
Theoretical Molecular Weight is 190-195 kDa

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: POLR1A

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition

Long Name

DNA-directed RNA polymerase I subunit RPA1

Alternate Names

A190, RPA194

Gene Symbol

POLR1A

Additional POLR1A Products

Product Documents for POLR1A Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for POLR1A Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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