PDGF-AA Antibody [mFluor Violet 500 SE]
Novus Biologicals, part of Bio-Techne | Catalog # AF1055MFV500
Conjugate
Catalog #
Key Product Details
Species Reactivity
Rat
Applications
Immunohistochemistry, Western Blot, Neutralization
Label
mFluor Violet 500 SE (Excitation = 410 nm, Emission = 501 nm)
Antibody Source
Polyclonal Goat IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
E. coli-derived recombinant rat PDGF-AA
Ser87-Arg196
Accession # AAB59693
Ser87-Arg196
Accession # AAB59693
Specificity
Detects rat PDGF‑AA in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant rat (rr) PDGF-AB is observed, 30% cross-reactivity with recombinant human PDGF-AA is observed, and less than 5% cross-reactivity with rrPDGF-BB is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for PDGF-AA Antibody [mFluor Violet 500 SE]
Application
Recommended Usage
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Neutralization
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: PDGF-AA
PDGF-AA (Platelet-Derived Growth Factor AA) is a widely expressed protein that forms disulfide linked homodimers or heterodimers with PDGF-B. PDGF-AA is expressed by monocytes, macrophages, fibroblasts, vascular smooth muscle cells, and vascular endothelial cells. It acts principally as a chemoattractant and inducer of protein synthesis in multiple cell types. PDGF-AA binds and signals through homodimers of the receptor tyrosine kinase PDGF R alpha which itself associates with FGF R1 and Neuropilin-1. PDGF-AA additionally signals through heterodimers of PDGF R alpha and PDGF R beta.
Long Name
Platelet-derived Growth Factor AA
Alternate Names
PDGFAA
Gene Symbol
PDGFA
Additional PDGF-AA Products
Product Documents for PDGF-AA Antibody [mFluor Violet 500 SE]
Product Specific Notices for PDGF-AA Antibody [mFluor Violet 500 SE]
mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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