PDGF-AA Antibody (114506) [mFluor Violet 450 SE]
Novus Biologicals, part of Bio-Techne | Catalog # FAB221MFV450
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Neutralization
Label
mFluor Violet 450 SE (Excitation = 406 nm, Emission = 445 nm)
Antibody Source
Monoclonal Mouse IgG1 Clone # 114506
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
E. coli-derived recombinant human PDGF-AA
Ser87-Thr211
Accession # P04085
Ser87-Thr211
Accession # P04085
Specificity
Detects human PDGF-AA in direct ELISAs. In direct ELISAs, approximately 20% cross-reactivity with recombinant human (rh) PDGF-AB is observed and no cross-reactivity with rhPDGF-BB, rhPlGF, rhVEGF206, rhVEGF B186, rhVEGF C, rhVEGF D, or rhCTGF is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for PDGF-AA Antibody (114506) [mFluor Violet 450 SE]
Application
Recommended Usage
Neutralization
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: PDGF-AA
PDGF-AA (Platelet-Derived Growth Factor AA) is a widely expressed protein that forms disulfide linked homodimers or heterodimers with PDGF-B. PDGF-AA is expressed by monocytes, macrophages, fibroblasts, vascular smooth muscle cells, and vascular endothelial cells. It acts principally as a chemoattractant and inducer of protein synthesis in multiple cell types. PDGF-AA binds and signals through homodimers of the receptor tyrosine kinase PDGF R alpha which itself associates with FGF R1 and Neuropilin-1. PDGF-AA additionally signals through heterodimers of PDGF R alpha and PDGF R beta.
Long Name
Platelet-derived Growth Factor AA
Alternate Names
PDGFAA
Gene Symbol
PDGFA
Additional PDGF-AA Products
Product Documents for PDGF-AA Antibody (114506) [mFluor Violet 450 SE]
Product Specific Notices for PDGF-AA Antibody (114506) [mFluor Violet 450 SE]
mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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