Nogo-A Antibody [mFluor Violet 500 SE]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-41070MFV500
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence
Label
mFluor Violet 500 SE (Excitation = 410 nm, Emission = 501 nm)
Antibody Source
Polyclonal Rabbit IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Antibody was raised against a 23 amino acid synthetic peptide from near the amino terminus of human NogoA. The immunogen is located within the first 50 amino acids of NogoA. Amino Acid Squence: SDSPPRPQPAFKYQFVREPEDEE
Specificity
At least five isoforms of Nogo are known to exist; this antibody is specific for NogoA.
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Applications for Nogo-A Antibody [mFluor Violet 500 SE]
Application
Recommended Usage
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Immunocytochemistry/ Immunofluorescence
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Peptide affinity purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Nogo-A
Nogo-A, also known as Reticulon 4 (RTN4) is a transmembrane protein that is mainly expressed in oligodendrocytes of the central nervous system but is also reported in fibroblasts, dorsal root ganglion neurons, macrophages, and myoblasts. Binding of the Nogo66 region to the Nogo Receptor/p75 complex on axons induces growth cone collapse and blocks neurite outgrowth. Nogo-A interactions with the Nogo-B receptor (NgBR/NUS1) can regulate vascular remodeling, inhibit neuronal differentiation, and promote glial formation from neural progenitors.
Long Name
Reticulon 4A
Alternate Names
NI220, NogoA, RTN4, RTN4A
Gene Symbol
RTN4
Additional Nogo-A Products
Product Documents for Nogo-A Antibody [mFluor Violet 500 SE]
Product Specific Notices for Nogo-A Antibody [mFluor Violet 500 SE]
mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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