NKX2.2 Antibody (CL11380) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21191

Novus Biologicals, part of Bio-Techne
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NBP3-21191-25ul
NBP3-21191-100ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL11380

Format

BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NKX2.2 Antibodies »

Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from O95096, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Novus Biologicals Mouse NKX2.2 Antibody (CL11380) - BSA Free (NBP3-21191) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for NKX2.2 Antibody (CL11380) - BSA Free

Immunohistochemistry-Paraffin: NKX2.2 Antibody [NBP3-21191] -

Immunohistochemistry-Paraffin: NKX2.2 Antibody [NBP3-21191] -

Staining of human Liver shows no positivity in hepatocytes as expected.
Western Blot: NKX2.2 Antibody [NBP3-21191] -

Western Blot: NKX2.2 Antibody [NBP3-21191] -

Analysis in human cell line U-138MG.
Immunohistochemistry-Paraffin: NKX2.2 Antibody [NBP3-21191] -

Immunohistochemistry-Paraffin: NKX2.2 Antibody [NBP3-21191] -

Staining of human Stomach shows strong nuclear positivity in enteroendocrine cells.
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Applications for NKX2.2 Antibody (CL11380) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NKX2.2

Nkx2.2, or Homeobox protein Nkx-2.2, consists of a 273 amino acid isoform that is 30 kDa, and is involved in controlling and maintaining the expression of genes within pancreatic endocrine cells and axons. Current research is being conducted on the relationship between Nkx2.2 and a variety of diseases and disorders, including glioma, neuronitis, maturity-onset diabetes, pancreatitis, Partington syndrome, sarcoma, gastrointestinal neuroendocrine tumor, acute lymphoblastic leukemia, multiple sclerosis, and carcinoid tumors. The protein has been linked to the Wnt, Hedgehog, and notch pathways, as well as regulation of beta-cell development and gene expression. NKx2.2 interacts with several other proteins, including OLIG2, HDAC1, SIN3A, FOXA2, and FOXO1.

Long Name

NK2 Homeobox 2

Alternate Names

NKX2B

Gene Symbol

NKX2-2

Additional NKX2.2 Products

Product Documents for NKX2.2 Antibody (CL11380) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NKX2.2 Antibody (CL11380) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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