Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 448406

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MP1 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human MP1
Ala2-Ser124
Accession # Q9UHA4

Specificity

Detects human, mouse, and rat MP1 in Western blots.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for MP1/MAP2K1IP1 Antibody (448406) [DyLight 405]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MP1

The function of MAP2K1IP1/MAPKSP1 (MP1;MEK partner-1) a 14kDa scaffold protein, is to bind specifically to MEK1 and ERK1 and bring them in close proximity in order to facilitate their activation. Localized to the late endosome, MAP2K1IP1 also interacts with an adaptor protein p14. While the interaction between MAPKSP1-ERK1 can take place in the absence of the adaptor protein p14, it is strengthened in the presence of p14. Additionally, it has been suggested that the binding of MAP2K1IP1/MAPKSP1 to MEK1 resides in a proline-rich sequence (residue 270-307) of MEK1.

Long Name

MEK-binding Protein 1

Alternate Names

LAMTOR3, MAP2K1IP1, Mapbp

Gene Symbol

LAMTOR3

Additional MP1 Products

Product Documents for MP1/MAP2K1IP1 Antibody (448406) [DyLight 405]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for MP1/MAP2K1IP1 Antibody (448406) [DyLight 405]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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