MKK3/MKK6 Antibody (275922) [Janelia Fluor® 646]
Novus Biologicals, part of Bio-Techne | Catalog # FAB2514J
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human, Mouse, Rat
Applications
Western Blot
Label
Janelia Fluor 646
Antibody Source
Monoclonal Mouse IgG1 Clone # 275922
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
E. coli-derived recombinant human MKK3
Met1-Ser347
Accession # P46734
Met1-Ser347
Accession # P46734
Specificity
Detects human MKK3/MKK6 in direct ELISAs and recombinant and endogenous MKK3/MKK6 in Western blots.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for MKK3/MKK6 Antibody (275922) [Janelia Fluor® 646]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: MKK3/MKK6
Mitogen-activated protein kinase kinase 3 (MKK3), also known as MEK3, and the closely related MKK6 are activated by proinflammatory cytokines and environmental stresses. Activation occurs through phosphorylation by several upstream MAPK kinase kinases, including ASK1 and TAK1. Both MKK3 and MKK6 are dual specificity protein kinases, phosphorylating and activating the p38 MAP kinases at Thr and Tyr positions within the phosphoacceptor sequence Thr-Gly-Tyr.
Long Name
Mitogen-activated Protein Kinase Kinase 3
Alternate Names
Dual specificity mitogen-activated protein kinase kinase 6;MAP2K6;MAPKK6;MEK6;MKK6;PRKMK6;SAPKK3;SAPKK-3
Additional MKK3/MKK6 Products
Product Documents for MKK3/MKK6 Antibody (275922) [Janelia Fluor® 646]
Product Specific Notices for MKK3/MKK6 Antibody (275922) [Janelia Fluor® 646]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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