mGluR4 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-47474

Novus Biologicals, part of Bio-Techne
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NBP3-47474
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all mGluR4 Antibodies »

Product Specifications

Immunogen

metabotropic glutamate receptor 4. (Uniprot# Q14833)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit mGluR4 Antibody - BSA Free (NBP3-47474) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for mGluR4 Antibody - BSA Free

mGluR4 Antibody - BSA Free

Western Blot: mGluR4 Antibody - BSA Free [NBP3-47474] -

Western Blot: mGluR4 Antibody - BSA Free [NBP3-47474] - Mouse brain were subjected to SDS PAGE followed by western blot with (mGluR4 antibody) at dilution of 1:1000
mGluR4 Antibody - BSA Free

Immunohistochemistry: mGluR4 Antibody - BSA Free [NBP3-47474] -

Immunohistochemistry: mGluR4 Antibody - BSA Free [NBP3-47474] - Immunohistochemistry of paraffin-embedded rat brain using (mGluR4 antibody) at dilution of 1:100

Applications for mGluR4 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50-1:500

Western Blot

1:500-1:2000
Application Notes
Theoretical Molecular Weight is 87 kDa, 101 kDa

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: mGluR4

The Metabotropic Glutamate Receptor mGluR4/GRM4 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group III includes GRM4, GRM6, GRM7, and GRM8 receptors that are linked to the inhibition of the cyclic AMP signaling cascade. Two protein isoforms have been reported in rat (mGluR4a 912 aa; mGluRb 983 aa), which differ at the C-terminus. GRM4 has been reported in various regions of the brain, eye, and spinal cord. ESTs have been isolated from brain, embryo, melanocyte/uterus/fetal heart, nerve, and testis libraries. Caution: GLUR4 refers to Ionotropic Glutamate Receptor 4, not to Metabotropic Glutamate Receptor 4 (mGLUR4).

Long Name

Metabotropic Glutamate Receptor 4

Alternate Names

GPRC1D, GRM4

Gene Symbol

GRM4

Additional mGluR4 Products

Product Documents for mGluR4 Antibody - BSA Free

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Certificate of Analysis

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Product Specific Notices for mGluR4 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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