Macrophage and Histiocytoma Marker Antibody (D11) [PE]

PE (Excitation = 488 nm, Emission = 575 nm)

Monoclonal Mouse IgG₁ kappa Clone # D11

Please see the vial label for concentration. If unlisted please contact technical services.

Membrane preparation from human hepatocytes

Does not react with Mouse, Rat or Porcine.

Cell Surface & Cytoplasmic

In Western blotting, it detects an antigen of 125kDa in human liver and 135kDa in tumors of histiocytic origin. Comparative study of this monoclonal antibody and a standard CD68 monoclonal antibody showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This monoclonal antibody shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This monoclonal antibody does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.

Macrophage & Histiocytoma Marker

Monoclonal

Mouse

IgG₁ kappa

Protein A or G purified

PBS

0.05% Sodium Azide

Please see the vial label for concentration. If unlisted please contact technical services.

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C in the dark.