LRIG1 Antibody (789211) [DyLight 680]
Novus Biologicals, part of Bio-Techne | Catalog # FAB7498Y
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry, Flow Cytometry, Immunocytochemistry, CyTOF-ready
Label
DyLight 680 (Excitation = 692 nm, Emission = 712 nm)
Antibody Source
Recombinant Monoclonal Mouse IgG2B Clone # 789211
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
HEK293 human embryonic kidney cell line transfected with human LRIG1
Ala35-Ser779
Accession # Q96JA1
Ala35-Ser779
Accession # Q96JA1
Specificity
Detects human LRIG1 in ELISAs.
In direct ELISAs, less than 5%
cross-reactivity with recombinant mouse LRIG1 and recombinant human LRIG3 is
observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Applications for LRIG1 Antibody (789211) [DyLight 680]
Application
Recommended Usage
CyTOF-ready
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Immunocytochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: LRIG1
LRIG1 (leucine-rich repeat and Ig-like domain-containing-1) is a 145 kDa type I transmembrane glycoprotein that shares 45 - 50% amino acid (aa) identity with two other mammalian LRIG proteins. LRIG1 shows highest expression in subsets of glial cells in brain, and certain epithelia in liver, stomach, small intestine and skeletal muscle. Within the cell, LRIG1 is expressed in the perinuclear region as well as on the surface. LRIG1 binds ErbB receptors and promotes their ubiquitination, internalization and destruction.
Long Name
Leucine-rich Repeats and Immunoglobulin-like Domains 1
Alternate Names
Img, LIG1
Gene Symbol
LRIG1
Additional LRIG1 Products
Product Documents for LRIG1 Antibody (789211) [DyLight 680]
Product Specific Notices for LRIG1 Antibody (789211) [DyLight 680]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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